Drugs used in nematodozah. R02SE01 - protyhelmintni drugs. Side effects and complications by the drug: headache, insomnia, dizziness, cramps, sensation of palpitations, indigestion effects (nausea, vomiting, abdominal pain, diarrhea), with a long reception possible nausea, vomiting, dyspeptic disorders, anorexia, pancreatitis, olfactory and gustatory hallucinations, nervousness, anxiety, headaches, insomnia, paresthesia, peripheral polyneuropathy, speech disorders, with-m, similar to encephalopathy (in patients with the post-mortem arthritis and intestinal parasitosis), flu-like s-m (chills, fever, nausea, weakness), mouth ulcers, thrombocytopenia, agranulocytosis, renal (creatinine concentration increase in the blood), liver dysfunction, AR (skin itching, rash, urticaria), increased cholesterol levels, myalgia, arthralgia. than ankilostomoyu (Necator americanus). Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pregnancy, lactation, children under 6 months, concurrent use piperazynu. Dosing and Administration of drugs: internally, with trichinosis - adults and teenagers - to 200-400 mg 3 was a day for 3 days and from 4 to 10 days to 400-500 mg 3 was a day when stronhiloyidozi - recommend adults take 200 mg 2 g / day for 3 days, Upper Gastrointesinal older than 2 years - 100 mg 2 g / post-mortem also for 3 days during treatment should not follow the diet and use laxatives, repeat the treatment if in 3 weeks again ' are signs of helminthiasis, with dirofilyariozi - 100 mg 2 g / day for 3 days. Method of production of drugs: Table. Side effects of drugs and complications in the use of drugs: in some cases (especially in the excretory kidney function) - muscle weakness, tremors, euphoria, hallucinations, blurred vision, a violation of coordination, as well as diarrhea, nausea, spastic abdominal pain, headache. The main pharmaco-therapeutic effects of drugs: an effective tool protyhlysnyy, active in treating diseases caused by round worms; active against Enterobius vermicularis, Ascaris lumbricoides, Ankylostoma duodenale, Necator americanus, a moderate effect has on Trichocephalus trichiurus; depolarizing action causes the post-mortem neyromuskulyarnoho Left Ventricular Outflow Track sensitive to it, worms, As a result there helminth muscle spasm, loss of its ability to hold, and it is removed from the body laxation, Bone Marrow not irritate post-mortem mucous intestine and leads to migration of the worms; detrimental effect on the spread of parasites in the early phase of their development and mature form, but not acting on the pupae during their migration in tissues, is effective in invasions pinworm (Enterobius vermicularis) and eelworm (Ascaris lumbricoides); can be applied for invasions ankilostomoyu: more effective in the treatment of disease caused by duodenal ankilostomoyu (Ancylostoma duodenale), caused U.S. Piperazyn and its derivatives. Drugs used in nematodozah. Indications post-mortem use drugs: ascariasis; enterobioz. Indications for use drugs: enterobioz, ascariasis, ankilostomoz, nekatoroz. Side effects of drugs and complications in the use of drugs: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation, jaundice, insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, convulsions, decreased visual acuity; hemodyscrasia, itching, hives, pemphigus, dermatitis, fever. Method of production of drugs: Table., Coated tablets, 0,125 grams of 0,25 g; suspension for oral use, 0,25 g / 5 ml vial. Derivative tetrahidropirymidynu. After 1 week of treatment is repeated. Derivative imidazotiazolu. The main pharmaco-therapeutic effects of drugs: anthelminhic way to treat ascariasis and enterobiozu, with other nematodozah and when tsestodozah and trematodozah - inefficient, acting statevonezrili and mature individuals of both sexes helminths (ascaris and pinworm), causing paralysis of the muscles of the nematode, breaking function of their neuromuscular system after helminths removed peristaltic movements of intestines; degree dehelmintatsiyi 90 - 95%, and with repeated use reaches 100%. to chew 200 mg, 400 mg tab., film-coated, 200 mg, 400 mg for oral suspension 100 mg / 5 ml vial and 200mh/5ml. Pharmacotherapeutic group.
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