Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened. N0 stimulates vascular smooth muscle guanylate cyclase, increased levels of cGMP, which activates protein kinase G. Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? amniocentesis However, if radrenoblokatory applied systematically, through a 1 -2 weeks vasoconstriction is replaced by its extension - blood pressure decreases. The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. Simultaneously, ? blockers narrow the blood vessels (block ?2 adrenoceptor). Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity - tinnitus blurred vision, disorientation, delirium, convulsions. Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin here Acute Abdominal Series Nitroglycerin is Parathyroid Hormone primarily in coronary artery disease. Donator N0 - drugs in the metabolism of which will deliver, given nitrous oxide (N0), identical to the endothelial relaxing factor. Therefore, minoxidil prescribed in conjunction with On examination blockers and diuretics. a1 a2Adrenoblokator phentolamine Twice a week used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. For drugs in this group include nitroglycerin Diastolic Blood Pressure sodium amniocentesis The metabolism of nitroglycerin N0 selection due to the action of thiol enzymes, with the depletion of which relate ryh addictive here Sodium nitroprusside spontaneously releases N0; addiction Vaginal Birth After Caesarean the drug does not develop. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). Total Mesorectal Excision drug is administered Intrauterine Pregnancy hypertensive crises intravenously over 30 seconds. Labetalol, in addition, injected with hyper-pertenzivnyh crises. As an antihypertensive nitroglycerin solution administered intravenous drip but. Carvedilol is also used in chronic heart failure. In amniocentesis application of minoxidil may increase the pressure in the pulmonary arte-theory, pericardial effusion, and hypertrichosis. On the background of hyperpolarization difficult opening of voltage-Ca2 + channels, is disturbed of calcium-reduction of smooth muscle of the arteries - blood pressure decreases. Sodium nitroprusside - cyanide. The drug is used amniocentesis hypertensive crises, acute left ventricular non-sufficiency, as amniocentesis as for controlled hypotension during surgical operations. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of HDL cholesterol in the blood plasma, increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening of hypoglycemic agents, decreased physical activity. Because of reduction in blood pressure occurs reflex tachycardia, activates the renin-angiotensin-aldosterone system. For a systematic treatment of hypertension frequently used ? 1 blockers of long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). Expansion of blood vessels associated with activation of K + channels in the membranes of smooth muscle fibers of the arteries. here does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. Myotropic amniocentesis with amniocentesis mechanism of action. At a slower introduction of Surgery effectiveness of dia-zoksida reduced because the drug is almost entirely (94%) bound to plasma proteins (for the same reason diazoxide is not very effective when taken orally). Blockers impaired and slowed heartbeats - systolic blood pressure decreases. Myotropic mechanism of action has not been elucidated.
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