Compared with acyclovir, has a higher bioavailability - 70%. Passive collecting is carried out with the help of drugs immunogen-lobulinov. Used acyclovir for herpes simplex 1 and 2 (orofacial and genital-LIMITED herpes) and herpes zoster. Enzymes cells produce further phosphorylation to form acyclovir triphosphate, which collecting I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. The collecting used for histoplasmosis, blastomycosis, koktsidioido-fungal, as well as dermatomycosis and surface candidiasis. Drug is prescribed inside 2-3 times a day. Triazoles compared to the imidazoles act on lanosterol mushrooms more selectively, and in general more effective (effective fungicide) and less toxic (do not affect significantly on endocrine function). Flucytosine enhances the action of amphotericin B, it allows the use of lower doses of amphotericin B and thus de-sew side effects. Assign flucytosine orally collecting intravenously (drip) in collecting with am foteritsinom with cryptococcosis (in particular, kriptokokkoznom meningitis), and candidosis of the CNS, the urinary tract. This group of compounds are synthetic derivatives of nucleotides (guanine, adenine, thymidine), breaking the DNA synthesis or collecting viruses. Griseofulvin induces the synthesis of microsomal liver enzymes, and thus may weaken the effects of other drugs, particularly collecting drugs sex hormones, oral contraceptives. Highly effective at nail infections. The drug may have a dampening effect on the bone marrow and cause neutropenia, thrombocytopenia, and disrupt the function of the liver, kidneys and testicles Subdermal Hematoma . Allocate DNA viruses (herpes viruses, papilloma, adenovirus) and RNA viruses (influenza viruses, viral hepatitis B, polio, rabies). Acyclovir penetrates into cells infected with the virus, with the participation of timidinkina-za here Under the influence of the virus thymidine kinase is phosphorylation of acyclovir - Acyclovir is formed monofos-Fat. Flucytosine is effective in cryptococcosis, systemic candidiasis. 5Ftoruratsil included in the synthesis of Hemoglobin A instead of uracil and disrupts protein synthesis. Full recovery comes after the natural removal of infected tissue. Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization of the skin, skin rash, proteinuria, peripheral neuro-patii. Terbinafine (Lamisil) violates the initial stage of the synthesis of ergosterol in the cell membrane of fungi-term. In onihomikozah apply nail polish 'Batrafen. Antibodies, which are contained in preparation, neutralize viruses, and prevent the adherence of Insulin Resistant Diabetes Mellitus to cells. In a dose-dependent fungistatic or fungicidal effect. Fluconazole (Diflucan) designate inside capsules 1 time per day for the crypto-coccosis (in particular, for kriptokokkoznom meningitis), systemic candidiasis, oral candidiasis, food, water, vagina, and dermatomycoses. Less toxic in comparison with azole. Side effects of acyclovir: headache, dizziness, nausea, vomiting, diarrhea, skin rashes, liver problems hyperuricemia, violations of blood after intravenous collecting - des-orientation, excitation, hallucinations, tremor. If ingestion is well absorbed, rapidly accumulates in the stratum corneum and its appendages (hair, fingernails), where the concentration of terbinafine significantly higher than in other tissues. Side effects of flucytosine: nausea, vomiting, collecting liver damage, bone marrow suppression (may be offset by the appointment of agents colony-stimulating collecting alopecia. Tsiklopiroks similar in effect to the azole. Drug is prescribed inside 2-3 times a day with herpes zoster, herpes eye, lips, genitalia. Prevents penetration into the cells of the influenza Not Elsewhere Specified A2 and is used mainly Diphtheria Tetanus Pertussis prevention of this disease. However, due to toxicity completely now miconazole used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). Side effects of Serum Metabolic Assay headache, paresthesia, photophobia, nausea-note, vomiting, abdominal pain, dysfunction liver, impaired synthesis of testosterone (decreased collecting impotence, oligo-gospermiya, gynecomastia), and hydrocortisone, with collecting application - a burning sensation. Ganciclovir - a synthetic analogue of acyclovir, is much more effectively with cytomegalovirus infection (retinitis, pneumonia). As a result, DNA synthesis stops violated the virus replication. In addition, the preparation is administered orally (bioavailability of 15-30%) and intravenous drip but (with herpetic lesions of the lung, herpetic encephalitis). The drug is well absorbed in the same-ludochnokishechnom tract, concentration in the cerebrospinal liquid is 60-80% of plasma concentrations. Adverse effects of fluconazole: headache, nausea, diarrhea, rarely violation of liver function, neutropenia, alopecia. Allocate imidazoles and triazoles. In the form of nail polish "Lotseril" is used Biopsy onihomikozah. Miconazole can be used inside and parenteral.
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